Amy Poehler, who plays Mrs. George, is only seven years older than her on-screen daughter, Rachel McAdams (Regina George).
The film cast includes four SNL cast members: Tina Fey, Ana Gasteyer, Amy Poehler and Tim Meadows.
This was the feature film screenwriting debut for Tina Fey.
Regina means “queen,” in Latin, which is why the name was chosen for the Queen Bee.
Rachel McAdams didn’t dye her hair blonde for the film. She wore a wig.
The skirts for the Christmas talent show are made of plastic; the costume designer says they were made of that material to “represent the Plastics.”
To film one of the scenes, Amy Poehler
(Mrs. George) pinned a piece of cocktail wiener into her bra to encourage the chihuahua dog to nibble there.
This movie nearly earned an R rating for explicit, risqué gags and jokes, which were subsequently cut.
There’s a MEAN GIRLS video game: It’s a “single-player puzzle game and allows the player to combine similarly coloured jewels, shoes and lipstick. Chain combinations together and you can unleash rumours, pranks and put-downs.”